Over the years, medical science has been continuously evolving to accommodate any changes in the medical landscape. It does not cease from looking for solutions and treatments of various diseases. The discovery of liposome is among the most remarkable breakthroughs in the industry. This is used to aid drug intake to enhance its efficiency, increase success rate in organ transplant surgery and treat several medical malfunctions.
The liposomes are tiny, microscopic vesicles which are produced and developed in laboratories. These are made of phospholipids, which are extracted from other sources or produced by natural means. The outer wall of the vesicles has similar composition as a cell wall. Hence, it can interact with the cells directly. These tiny, sphere-shaped bubbles typically have watery core.
The most common use of this structure is to introduce medicines to the patient's body more effectively. The unique property of the vesicles allow drugs to be delivered in specific parts of the body through diffusion. With its double-layered membranes, the vesicle can carry hydrophobic drugs. This can also be used to carry biological agents like antibodies to targeted parts in the patient's body.
The spheroid bubbles can also extend the delivery time for the drugs while keeping its potency. The bi-layered bubble slowly releases the drugs over a span of time. Thus, side-effects may be reduced. Since the vesicle only releases the medication to the affected tissues, it can also help maximize the effects of the drugs.
The vesicles are also believed to be an effective cancer fighting agent. The spheroids can mark the cancer cells. It can also slip right to the tumor by going through the blood flow. This stays in the bloodstreams as well because of its miniature size and its property that is similar to the blood vessels. The drug vessels cannot pass through the endothelial wall as opposed to cancer cells, which are naturally leaky.
This can also help fight autoimmune diseases. In most transplant surgeries, the body initially identifies the newly transplanted organ as a foreign object. As a result, the immune system will try to attack it as the body's natural reaction to protect itself from infestation. This can lead to the body's rejection of the harvested organ. The artificial lipid can help suppress the immune system to slow down its progression.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
These vesicles come in various sizes. The vessels are typically small for the white blood cells to easily engulf the bubbles before the drug it carries can be released. Prior to its production, the size and numbers of vesicles to be created have to be determined. Possibilities of reproduction must also be anticipated.
The only possible disadvantage with liposome is the cost of producing it. Mass production is not currently feasible because the vessels do not last long following its creation. Stability may also be an issue. On occasion, the drugs may be mixed unintentionally. Other than that, this is a promising breakthrough.
The liposomes are tiny, microscopic vesicles which are produced and developed in laboratories. These are made of phospholipids, which are extracted from other sources or produced by natural means. The outer wall of the vesicles has similar composition as a cell wall. Hence, it can interact with the cells directly. These tiny, sphere-shaped bubbles typically have watery core.
The most common use of this structure is to introduce medicines to the patient's body more effectively. The unique property of the vesicles allow drugs to be delivered in specific parts of the body through diffusion. With its double-layered membranes, the vesicle can carry hydrophobic drugs. This can also be used to carry biological agents like antibodies to targeted parts in the patient's body.
The spheroid bubbles can also extend the delivery time for the drugs while keeping its potency. The bi-layered bubble slowly releases the drugs over a span of time. Thus, side-effects may be reduced. Since the vesicle only releases the medication to the affected tissues, it can also help maximize the effects of the drugs.
The vesicles are also believed to be an effective cancer fighting agent. The spheroids can mark the cancer cells. It can also slip right to the tumor by going through the blood flow. This stays in the bloodstreams as well because of its miniature size and its property that is similar to the blood vessels. The drug vessels cannot pass through the endothelial wall as opposed to cancer cells, which are naturally leaky.
This can also help fight autoimmune diseases. In most transplant surgeries, the body initially identifies the newly transplanted organ as a foreign object. As a result, the immune system will try to attack it as the body's natural reaction to protect itself from infestation. This can lead to the body's rejection of the harvested organ. The artificial lipid can help suppress the immune system to slow down its progression.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
These vesicles come in various sizes. The vessels are typically small for the white blood cells to easily engulf the bubbles before the drug it carries can be released. Prior to its production, the size and numbers of vesicles to be created have to be determined. Possibilities of reproduction must also be anticipated.
The only possible disadvantage with liposome is the cost of producing it. Mass production is not currently feasible because the vessels do not last long following its creation. Stability may also be an issue. On occasion, the drugs may be mixed unintentionally. Other than that, this is a promising breakthrough.
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